Noids bad for you?

I've seen a lot of articles and threads that say noids are bad for you. Sure if you over do your brain will short out. And WDs are no fun. But is there any damage to your overall health? Any long term side-effects?

Their research chems man nobody knows!

Yeah a lot of people complain about horrible chronic chest pains and since they are basically not tested for safety at all in any significant way, they could do virtually anything over a long period of time. The effects of chronic use over time are not known since most of these chemicals have only been out for a couple years but it is pretty clear that they are quite bad for you.

Since tolerance to noids build so quickly and due to their incredibly addictive nature, overdosing is a pretty big possibility since you'd need to increase your dose to achieve the desired effects.

However, every compound is different, some people report no addictive effects from certain noids and some are quite mild. Given their death toll relative to their to how long they have been available, I would say yes, Noids are quite bad for you.

Honestly the range of weird and extreme side effects that I've seen from noids and the fact that they're

synthetic

full agonists

while the only known natural "safe" agonist is a partial agonist

lead me to conclusion that noids are more unpredictable, dangerous and possibly harmful than majority of other RC groups, on par with RC opioids, which have their danger rank boosted by their addictivity.

Yes the problem is the labs synthesizing and companies selling these have very poor (if any) quality control so you aren't necessarily getting what it says the compound is. Additionally we know very little about what else these drugs hit aside from cannabinoid receptors so toxicity could have another mechanism. But yeah, cardiotoxity, pulmonary edema, seizures all of which can and have lead to death.

Also these compounds are high affinity high efficacy cb1 agonists and will cause a lot of tolerance forcing you to increase your dose which increases activity at off target sites.

Just don't do the stuff. It's not worth it.